Tissue Lysates
Cayman Chemical S-CCG-1423 100ug
A stereoisomer of CCG-1423 that more potently inhibits MRTF-A-dependent cellular events, including SRF-mediated gene expression and cell migration
Cayman Chemical 4 S 11 R-DIHDoHE 100UG
A dihydroxy-DHA derivative whose biological actions have not yet been determined
Cayman Chemical tetrnor-MIsoprostol 100ug
A metabolite of misoprostol; formed when misoprostol undergoes rapid de-esterification to form misoprostol (free acid), which is further metabolized to form the more polar tetranor-misoprostol in rats, dogs, and monkeys
Cayman Chemical PtdIns 5P11 2dIpalmItoy 100UG
A synthetic analog of natural PtdIns featuring C16:0 fatty acids at the sn-1 and sn-2 positions; contains the same inositol and DAG stereochemistry as that of the natural compound
Cayman Chemical 9 S-HODE-13C18 100ug
An internal standard for the quantification of 9-HODE by GC- or LC-MS
Cayman Chemical -AeroplysInIn-1 100ug
A sea sponge metabolite with diverse biological activities; induces cell death in MCF-7 and ZR-75-1 human breast cancer cells in a time- and concentration-dependent manner from 0.25-0.5 μM; blocks EGF-induced endocytosis of EGFR and EGF-dependent cell proliferation in MCF-7 cells; inhibits BAE cell proliferation and cord formation in a Matrigel™ assay; inhibits angiogenesis in a CAM assay from 1.5-3 nmol per egg; has antibacterial activity against Gram-positive bacteria; inhibits HIV-1 replication (IC50 = 14.6 μM)
Cayman Chemical 16 17-DIHDPA 100ug
A DHA metabolite that inhibits VEGF-induced angiogenesis and reduces cancer cell metastasis in mice
Cayman Chemical 19 20-EDP EthnolamIde 100ug
An ω-3 endocannabinoid epoxide and CB receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively); reduces the viability of 143B metastatic osteosarcoma cells at 25 µM; decreases the production of IL-6 and increases LPS-induced production of IL-10 in BV-2 microglia at 2.5-10 µM; decreases LPS-induced cytotoxicity in BV-2 microglia at 5-10 µM; decreases nitrite production at 7.5 µM, an effect that can be partially reversed by AM630 and GW 9662; induces vasodilation of isolated preconstricted bovine coronary arteries (ED50 = 1.9 µM); tube formation by HMVECs
Cayman Chemical 5-OxoETE methyl ester 100ug
An esterified form of 5-oxoETE; an agonist of OXER1 (EC50 = 1.54 µM) that has a higher maximal response than 5-oxoETE in a β-arrestin assay
Cayman Chemical PDL1 EXrAClular DomaInh 100ug
Source: Recombinant C-terminal mouse IgG1 Fc-tagged human PD-L1 expressed in HEK293 cells • Amino acids: 19-239 • MW: 51.7 kDa
Cayman Chemical CalretIculInhumnrecombIn 100ug
Source: Recombinant human calreticulin expressed in HEK293 cells • Amino acids: 18-413 • MW: 45.99 kDa
Cayman Chemical 9 10-NItroleate 100ug
A mixture of 9-nitrooleate and 10-nitrooleate; induces transactivation of PPARγ or Nrf2 in reporter assays using MCF-7 cells at ≥0.3 and ≥3 µM, respectively; induces transactivation of PPARγ, PPARδ, or PPARα in reporter assays using CV-1 cells; induces adipogenesis in 3T3-L1 preadipocytes and glucose uptake in differentiated 3T3-L1 adipocytes at 3 µM; decreases ischemia-induced increases in plasma levels of blood urea nitrogen, creatinine, and TNF-α and kidney levels of Mpo and IL-1β and reduces tubular necrosis and tubule dilation in a mouse model of renal ischemia-reperfusion injury at 500 UG/kg every six hours for 24 hours
Sino Biological Recombinant Human Her2/ERBB2 Protein (Site-Specific AF 488 Conjugation, ECD, His Tag)
A DNA sequence encoding the extracellular domain (Met1-Thr652) of human ERBB2 (NP_004439.2) was expressed with a C-terminal polyhistidine tag. The protein is site-specifically conjugated with AF 488 (Excitation Max.= 495 nm, Emission Max.= 519 nm).